Urinary D-arabinitol/L-arabinitol levels in infants undergoing long-term antibiotic therapy.
نویسندگان
چکیده
Long-term antibiotic therapy is one of the main risk factors for mycosis. The urinary D-arabinitol/L-arabinitol (D-/L-ARA) ratio (a biomarker of several Candida species) was determined by gas chromatography with an electron capture detector in samples from 51 infants undergoing long-term antibiotic therapy. Although 47 of these children had higher D-/L-ARA ratios than healthy controls (P<0.0003), their values nonetheless remained within upper-normal limits (D-/L-ARA ratio of <3.6). Four children with suspected invasive candidiasis had above-normal ratios that normalized with fluconazole treatment.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 43 10 شماره
صفحات -
تاریخ انتشار 2005